Scientist-Cellular Genomics

Company: Joul--
Location: Cambridge
Posted on: April 10, 2025

Job Description:

Job Title: Scientist-Cellular Genomics

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Location: Cambridge, MA
Type: Contract

Overview
Leading pharmaceutical company looking for an experienced Scientist. Ideal candidates should have 3+ years of hands-on experience with immunoprofiling technologies and primary immune cells.

Responsibilities Follow existing lab standard operating procedures to: Participate in sample collection of murine and human tissues, including the preparation of tubes, interfacing with in vivo scientists to retrieve samples, isolation of primary immune cells, and standard mammalian cell culture
Participate in sample preparation of murine and human tissues, including tissue fixation, dissociation, sectioning, and antibody staining
Generate spatial and single-cell data via a number of commercial workflows, including 10x Genomics and Parse Technologies
Interpret quality control metrics for spatial, single-cell and cytometry experiments




ORGANIZATIONAL RELATIONSHIPS: Reports to a scientific director of the Systems Immunology Lab
Collaborates with and supports several multi-disciplinary experimental teams on a per-project basis



Requirements
EDUCATION AND EXPERIENCE: Masters + 3 years of experience in Biology, Immunology, or a related field

or Ph'D +0 yrs experience in Biology, Immunology, or a related field


TECHNICAL SKILLS REQUIREMENTS: 3+ years of hands-on experience with standard immunoprofiling technologies, including Flow Cytometry
Single-cell library preparation (ideally 10x Genomics or Parse Technology)
Preparation and loading of Illumina sequencing libraries
Bonus: generation of spatial transcriptomics data (any technology)


3+ years of experience with primary immune cells, including Primary immune cell isolation
Maintenace of immune cell lines
Cell culture and in vitro stimulation of primary immune cells


Bonus: experience with CRISPR mediated functional genomics, including electroporation of primary immune cells



Benefits
System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.




Ref: #568-Clinical

Keywords: Joul--, Boston , Scientist-Cellular Genomics, Other , Cambridge, Massachusetts