Cell and Molecular Biology Research Scientist (Contract)

Company: Vertex
Location: Boston
Posted on: April 8, 2025

Job Description:

Job DescriptionCell and Molecular Biology Research Scientist, Vertex Pharmaceuticals (Boston)Vertex Pharmaceuticals is seeking a highly motivated and talented cell biologist to support drug discovery efforts and join our Research team located in Boston, MA. This individual will join a team of biologists to work in a collaborative setting and to independently execute sophisticated biological experiments. The ideal candidate will have experience with cell-based phenotypic assays, including work with complex cell types such as primary cells and iPSC derived systems. Preference will be given to candidates with a track record of innovation in the field of cell biology. The applicant must be a demonstrated team player, adaptable to changing needs and able to work closely and responsively within their team. The applicant will be part of a fast-paced drug discovery team. Excellent communication and people skills are required.Key Responsibilities:

• Conduct medium-throughput in vitro functional assays using human cell models (typically 384-well format).
• Support development of complex human cell models for target validation, proof of concept and mechanism of action studies.
• Perform cell and molecular biology techniques including immunohistochemistry, western blotting, qPCR, high content imaging and analysis, etc. for characterization of human in vitro.
• Analyze and present data results, and recommend courses of action based on datasets and discussions with biologists and chemists.
• Propose and develop innovative approaches to build new cell models and functional assays.
• Maintain excellent written documentation (e.g., electronic notebook).Minimal Requirements:
  • The ideal candidate will have a Ph.D. with 0-3 years postdoctoral experience in Cell Biology, Biological Engineering, or related field.
  • Strong technical background in tissue culture and sterile technique.
  • Experience with complex disease modeling, cell line editing/engineering, qPCR, western blot, flow cytometry, immunocytochemistry and immunofluorescence microscopy.
  • Experience culturing primary and immortalized myoblasts and myotubes is preferred.
  • Excellent troubleshooting and multi-tasking skills, attention to detail and ability to work independently.
  • Excellent communication skills and ability to work in a highly-collaborative team environment.
  • A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society.Pay Range: $50-$55/HR
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Keywords: Vertex, Boston , Cell and Molecular Biology Research Scientist (Contract), Other , Boston, Massachusetts