Research Sr. Scientist, Biochemistry, (GI2) Inflammation Drug Discovery

Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024

Job Description:

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's and . I further attest that all information I submit in my employment application is true to the best of my knowledge.Job DescriptionAt Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.About the Role:The Gastrointestinal and Inflammation (GI2) Drug Discovery Unit at Takeda is building a new team of experienced, innovative, and collaborative researchers to deliver an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a Research Scientist to join our biology and cross-functional discovery teams -and create novel drug candidates.Objective / Purpose:

• Generate and execute preclinical development strategies to support candidate selection and mechanistic characterization, facilitating efficient clinical validation of impactful medicines for patients with inflammatory and autoimmune disorders
• Apply deep scientific expertise in immunology and/or cell biology to creatively mature innovative novel concepts within our team, in matrixed collaboration with other Takeda scientists, and external partners. -
• Drive an inclusive, open, and effective culture in a fast-growing drug discovery group.Accountabilities: - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
  • Generate data packages supporting candidate selection and asset characterization based on subject matter expertise, technical literature, and awareness of current industry standards.
  • Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.
  • Collaborate productively within a matrixed structure, clearly communicate results, challenges, and impact in presentations and conversations with broad audiences. - Integrate data generated from other disciplines. - - -
  • Critically assess and identify vendors and appropriate contract research organizations to supplement internal nonclinical studies.
  • Think independently and creatively about novel therapies for patients suffering from immune driven disorders.Education & Competencies (Technical and Behavioral):
    • PhD degree with 2+ years industry experience, or MS with 8+ years' experience, or BS with 10+ years' experience.
    • Strong expertise and depth of knowledge in biochemical assay development and screening technologies (FP, AlphaLISA, TR-FRET, ELISA and etc)
    • Familiar with cell-based screening technologies as well as biophysical techniques for hit identification and hit characterization.
    • Experience developing and/or evaluating novel small molecule, biologic and/or nucleic acid therapeutics.
    • Experience with cell culture and cell-based assays is highly preferred
    • Keeps up with the up-to-date scientific advancement and literature (e.g. competitive landscape, new technology)This position is currently classified as onsite in Cambridge, MA. Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. -For Location:Boston, MAU.S. Base Salary Range:$133,000.00 - $209,000.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.---The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. -U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. -EEO StatementTakeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.LocationsBoston, MAWorker TypeEmployeeWorker Sub-TypeRegularTime TypeFull time

Keywords: Takeda Pharmaceutical, Boston , Research Sr. Scientist, Biochemistry, (GI2) Inflammation Drug Discovery, Other , Boston, Massachusetts