Senior Director, Oncology Research

Company: Flagship Pioneering
Location: Boston
Posted on: February 11, 2025

Job Description:

ProFound Therapeutics is discovering proteins hidden within the expanded human proteome to uncover novel drugs and drug targets, producing first-in-class medicines for a multitude of diseases. The company's ProFoundry Platform uses state-of-the-art protein detection technologies to systematically identify and validate proteins and dissect their therapeutic potential. The result is an ever-expanding database of tens of thousands of novel proteins, including their connectivity, functionality, and roles in health and disease. ProFound Therapeutics was founded in 2020 by Flagship Pioneering. For more information, please visit www.profoundtx.com.Position Overview:The Senior Director, Oncology Research will lead ProFound Therapeutics' oncology research programs, driving strategic initiatives and leading a team of world-class scientists to develop innovative cancer therapies. You will play an integral role in shaping our research strategy, advancing our oncology pipeline, and translating scientific discoveries into clinical applications. This position requires a deep understanding of oncology, strong leadership skills, and a proven track record of success in pharmaceutical or biotech research environments.Key Responsibilities:

• Strategic Leadership:
• Develop and implement the overall scientific vision and strategy for oncology research at ProFound Therapeutics.
• Identify, evaluate, and integrate emerging scientific trends and technologies in cancer research to drive innovation.
• Foster a culture of scientific excellence, collaboration, and innovation within the research team.
• Research Management:
• Lead, mentor, and inspire our team of highly skilled researchers, ensuring the successful execution of research projects.
• Oversee the design and execution of preclinical and translational research studies, ensuring scientific rigor and adherence to timelines and budgets.
• Collaborate with cross-functional teams, including clinical development, regulatory affairs, and business development, to align research objectives with company goals.
• Partnerships and Collaboration:
• Establish and maintain relationships with key academic institutions, research organizations, and industry partners to foster collaboration and enhance the company's research capabilities.
• Represent ProFound Therapeutics at scientific conferences, industry meetings, and with external stakeholders.
• Innovation and Intellectual Property:
• Drive innovation by identifying novel therapeutic targets, developing new methodologies, and advancing the understanding of cancer biology.
• Oversee the protection of intellectual property generated from research activities, including the preparation and filing of patent applications.
• Regulatory and Ethical Compliance:
• Ensure that all research activities are conducted in compliance with relevant regulatory guidelines and ethical standards.
• Maintain a high standard of data integrity, accuracy, and quality in all research outputs.Qualifications:
  • Ph.D., M.D., or equivalent degree in oncology, molecular biology, cancer biology, or a related field.
  • Minimum of 10 years of experience in oncology research within the biotech, pharmaceutical, or academic sectors, with at least 5 years in a leadership role.
  • Proven track record of scientific innovation and successful project leadership, including the advancement of therapeutic candidates from discovery through early clinical development.
  • Strong publication record in high-impact scientific journals.
  • In-depth understanding of cancer biology, molecular pathways, and therapeutic modalities, with an emphasis on biologics and immunotherapies, like ADC's and/or T-cell engagers.
  • Demonstrated ability to lead and mentor a diverse team of scientists.
  • Excellent strategic thinking, problem-solving, and decision-making skills.
  • Outstanding communication and presentation skills, with the ability to articulate complex scientific concepts to both technical and non-technical audiences.
  • Experience with regulatory requirements and guidelines for preclinical and clinical research.Values and Behaviors:We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort working in and contributing to a dynamic and cross-functional team environment. The level of the role will be commensurate with the education and years of experience of the identified candidate.At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.About Flagship:Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.If your experience is close to what we're looking for, please consider applying. Experience comes in many forms, skills are transferable, and passion goes a long way. We know that diverse backgrounds and experiences make for the best problem-solving and creative thinking, which is why we're dedicated to adding new perspectives to the team and encourage everyone to apply. We look forward to learning more about you.Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
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